{"id":6807,"date":"2025-09-02T15:45:35","date_gmt":"2025-09-02T06:45:35","guid":{"rendered":"https:\/\/aquaphotomics.com\/ja\/?page_id=6807"},"modified":"2025-09-18T13:32:04","modified_gmt":"2025-09-18T04:32:04","slug":"protein-analysis","status":"publish","type":"page","link":"https:\/\/aquaphotomics.com\/ja\/protein-analysis\/","title":{"rendered":"\u30bf\u30f3\u30d1\u30af\u8cea\u5206\u6790"},"content":{"rendered":"\n<p>\u6c34\u306e\u5206\u6790\u306f\u3001\u305d\u306e\u958b\u59cb\u4ee5\u6765\u3001\u8fd1\u8d64\u5916\u5206\u5149\u6cd5\u306e\u5206\u91ce\u306b\u5b58\u5728\u3057\u3066\u3044\u307e\u3057\u305f\uff08Hirschfeld 1985\u3001Grant\u3001Davies\u3001\u304a\u3088\u3073Bilverstone 1989\u3001Iwamoto\u3001Uozumi\u3001\u304a\u3088\u3073Nishinari 1987\u3001Maeda et al.1995\uff09\u3002\u3053\u308c\u3089\u306e\u521d\u671f\u306e\u7814\u7a76\u306f\u3001\u6c34\u30b9\u30da\u30af\u30c8\u30eb\u306e\u7279\u6027\u3092\u5206\u6790\u3057\u3066\u5229\u7528\u3057\u307e\u3057\u305f\u304c\u3001\u5206\u5b50\u30b7\u30b9\u30c6\u30e0\u304a\u3088\u3073\u751f\u7269\u5b66\u7684\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u3068\u3057\u3066\u306e\u6c34\u306e\u6982\u5ff5\u306f\u307e\u3060\u8003\u616e\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u6c34\u306f\u3001\u305d\u306e\u652f\u914d\u7684\u306a\u5438\u53ce\u306e\u305f\u3081\u306b\u3001\u8d64\u5916\u7dda\u304a\u3088\u3073\u8fd1\u8d64\u5916\u7dda\u5206\u5149\u6cd5\u306e\u300c\u6700\u5927\u306e\u6575\u300d\u3068\u3088\u304f\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u614b\u5ea6\u306b\u306f2\u3064\u306e\u7406\u7531\u304c\u3042\u308a\u307e\u3059\u3002\u9577\u3044\u9593\u3001\u751f\u7269\u79d1\u5b66\u3067\u306f\u6c34\u306f\u4e0d\u6d3b\u6027\u5a92\u4f53\u3068\u898b\u306a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u751f\u304d\u3066\u3044\u308b\u30d7\u30ed\u30bb\u30b9\u306f\u3001\u907a\u4f1d\u5b50\u3001DNA\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u4ee3\u8b1d\u7269\u3001\u307e\u305f\u306f\u4ed6\u306e\u5358\u4e00\u306e\u751f\u4f53\u5206\u5b50\u306e\u89b3\u70b9\u304b\u3089\u8aac\u660e\u3055\u308c\u307e\u3057\u305f\u3002\u5f53\u7136\u306e\u3053\u3068\u306a\u304c\u3089\u3001\u7814\u7a76\u624b\u6cd5\u306f\u3053\u308c\u3089\u306e\u751f\u4f53\u5206\u5b50\u306e\u69cb\u9020\u306b\u95a2\u9023\u3057\u305f\u4fe1\u53f7\u3092\u62bd\u51fa\u3059\u308b\u3053\u3068\u306b\u7126\u70b9\u3092\u5408\u308f\u305b\u3066\u304a\u308a\u3001\u8fd1\u8d64\u5916\u9818\u57df\u3067\u306f\u3001\u6c34\u306e\u652f\u914d\u7684\u306a\u5438\u5149\u5ea6\u304c\u305d\u308c\u3089\u306e\u5438\u53ce\u5e2f\u3092\u89b3\u5bdf\u3059\u308b\u305f\u3081\u306e\u969c\u5bb3\u3068\u898b\u306a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u6c34\u79d1\u5b66\u306e\u5206\u91ce\u306f\u904e\u53bb\u6570\u5341\u5e74\u3067\u5927\u304d\u306a\u9032\u6b69\u3092\u9042\u3052\u3001\u6c34\u306b\u95a2\u3059\u308b\u4e00\u822c\u7684\u306a\u898b\u89e3\u3068\u751f\u7269\u30b7\u30b9\u30c6\u30e0\u306b\u304a\u3051\u308b\u305d\u306e\u5f79\u5272\u3092\u5927\u304d\u304f\u5909\u3048\u307e\u3057\u305f\uff08Pollack\u3001Cameron\u3001\u304a\u3088\u3073Wheatley 2006\u3001Del Giudice\u3001Spinetti\u3001\u304a\u3088\u3073Tedeschi 2010\u3001Ball 2008b\u3001a\u3001Chaplin 2006\uff09\u3002\u73fe\u5728\u3001\u6c34\u306f\u6d3b\u6027\u6eb6\u5a92\u3068\u3057\u3066\u8a8d\u8b58\u3055\u308c\u3066\u304a\u308a\u3001\u305d\u306e\u69cb\u9020\u3092\u6eb6\u8cea\u306b\u9069\u5fdc\u3055\u305b\u3066\u9069\u5fdc\u3055\u305b\u307e\u3059\u3002\u751f\u7269\u5b66\u7684\u30b7\u30b9\u30c6\u30e0\u3067\u306f\u3001\u751f\u4f53\u5206\u5b50\u304a\u3088\u3073\u7d30\u80de\u30d7\u30ed\u30bb\u30b9\u306e\u30c0\u30a4\u30ca\u30df\u30af\u30b9\u306b\u304a\u3044\u3066\u7a4d\u6975\u7684\u306a\u5f79\u5272\u3092\u679c\u305f\u3059\u4e00\u7a2e\u306e\u751f\u4f53\u5206\u5b50\u3067\u3059\uff08Ball 2008a\u3001Tsenkova 2008\u3001 2009\u30012010\uff09\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image alignleft\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"116\" src=\"https:\/\/aquaphotomics.com\/ja\/wp-content\/uploads\/2018\/04\/alat2-872522_1920-300x116.jpg\" alt=\"\" class=\"wp-image-2935\" srcset=\"https:\/\/aquaphotomics.com\/ja\/wp-content\/uploads\/2018\/04\/alat2-872522_1920-300x116.jpg 300w, https:\/\/aquaphotomics.com\/ja\/wp-content\/uploads\/2018\/04\/alat2-872522_1920-768x298.jpg 768w, https:\/\/aquaphotomics.com\/ja\/wp-content\/uploads\/2018\/04\/alat2-872522_1920-1024x397.jpg 1024w, https:\/\/aquaphotomics.com\/ja\/wp-content\/uploads\/2018\/04\/alat2-872522_1920-360x140.jpg 360w, https:\/\/aquaphotomics.com\/ja\/wp-content\/uploads\/2018\/04\/alat2-872522_1920.jpg 1600w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n\n\n\n<p>\u3055\u307e\u3056\u307e\u306a\u751f\u4f53\u5206\u5b50\u3068\u6c34\u3068\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3064\u3044\u3066\u306e\u591a\u65b9\u9762\u306b\u308f\u305f\u308b\u30a2\u30af\u30a2\u30d5\u30a9\u30c8\u30df\u30af\u30b9\u306e\u7814\u7a76\u3092\u901a\u3058\u3066\u3001\u305d\u308c\u3089\u306e\u30c0\u30a4\u30ca\u30df\u30af\u30b9\u3068\u305d\u3053\u3067\u6c34\u304c\u679c\u305f\u3059\u91cd\u8981\u306a\u5f79\u5272\u306b\u3064\u3044\u3066\u306e\u898b\u8b58\u3092\u5f97\u307e\u3057\u305f\u3002\u3053\u306e\u5206\u91ce\u3067\u6700\u521d\u306b\u5fdc\u7528\u3055\u308c\u305f\u3082\u306e\u306e1\u3064\u306f\u3001\u30d7\u30ea\u30aa\u30f3\u30bf\u30f3\u30d1\u30af\u8cea\u7570\u6027\u4f53\u306e\u540c\u5b9a\u306b\u95a2\u3059\u308b\u3082\u306e\u3067\u3057\u305f\uff08Tsenkova et al.2004\uff09\u3002 \u9285\uff08Cu\uff09\u306e\u4ee3\u308f\u308a\u306b\u30de\u30f3\u30ac\u30f3\uff08Mn\uff09\u304c\u7d50\u5408\u3059\u308b\u3053\u3068\u304c\u3001\u30d7\u30ea\u30aa\u30f3\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u6a5f\u80fd\u4e0d\u5168\u306e\u5f62\u306b\u5909\u63db\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u306e1\u3064\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u6c34\u6eb6\u6db2\u4e2d\u306eMn\u304a\u3088\u3073Cu\u7d50\u5408\u7570\u6027\u4f53\u306e\u30a2\u30af\u30a2\u30d5\u30a9\u30c8\u30df\u30af\u30b9\u5206\u6790\u306b\u3088\u308a\u3001\u3001Mn\u306e\u7d50\u5408\u306f\u4e0d\u5b89\u5b9a\u5316\u3068\u7dda\u7dad\u5316\u306e\u4fc3\u9032\u3092\u5f15\u304d\u8d77\u3053\u3059\u306e\u306b\u5bfe\u3057\u3066\u3001Cu\u306e\u7d50\u5408\u306f\u6c34\u4e2d\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5b89\u5b9a\u6027\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u5225\u306e\u7814\u7a76\u3067\u306f\u3001\u30a2\u30df\u30ed\u30a4\u30c9\u7dda\u7dad\u306e\u5f62\u6210\u306b\u3064\u3044\u3066\u7814\u7a76\u3055\u308c\u307e\u3057\u305f\uff08Chatani et al.2014\uff09\u3002\u4e26\u884c\u3057\u3066\u884c\u308f\u308c\u305f\u7814\u7a76\u306b\u3088\u308a\u30012050\u301c2350 nm\u304a\u3088\u30731300\u301c1600nm\u306e\u30b9\u30da\u30af\u30c8\u30eb\u9818\u57df\u3067\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5c0f\u7e4a\u7dad\u5316\u306b\u3068\u3082\u306a\u3046\u5909\u5316\u304c\u89b3\u5bdf\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u7d50\u679c\u306b\u3088\u308a\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5f62\u614b\u5909\u5316\u30d7\u30ed\u30bb\u30b9\u5168\u4f53\u304c\u6c34\u5206\u5b50\u96c6\u5408\u5f62\u614b\uff08\u30de\u30c8\u30ea\u30c3\u30af\u30b9\uff09\u306e\u5909\u5316\u306b\u53cd\u6620\u3055\u308c\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\uff08Chatani et al.2014\uff09\u3002<\/p>\n\n\n\n<p>Ball, P. 2008a. \u201cWater as a biomolecule.\u201d&nbsp;&nbsp;<em>ChemPhysChem<\/em>&nbsp;9 (18):2677-2685.<\/p>\n\n\n\n<p>Ball, P. 2008b. \u201cWater as an active constituent in cell biology.\u201d&nbsp;&nbsp;<em>Chemical reviews<\/em>&nbsp;108 (1):74-108.<\/p>\n\n\n\n<p>Chaplin, M. 2006. \u201cDo we underestimate the importance of water in cell biology?\u201d&nbsp;&nbsp;<em>Nature Reviews Molecular Cell Biology<\/em>&nbsp;7 (11):861-866.<\/p>\n\n\n\n<p>Chatani, E., Y. Tsuchisaka, Y. Masuda, and R. Tsenkova. 2014. \u201cWater molecular system dynamics associated with amyloidogenic nucleation as revealed by real time near infrared spectroscopy and aquaphotomics.\u201d&nbsp;&nbsp;<em>PloS one<\/em>&nbsp;9 (7):e101997.<\/p>\n\n\n\n<p>Del Giudice, E., P.R. Spinetti, and A. Tedeschi. 2010. \u201cWater dynamics at the root of metamorphosis in living organisms.\u201d&nbsp;&nbsp;<em>Water<\/em>&nbsp;2 (3):566-586.<\/p>\n\n\n\n<p>Grant, A., A.M.C. Davies, and T. Bilverstone. 1989. \u201cSimultaneous determination of sodium hydroxide, sodium carbonate and sodium chloride concentrations in aqueous solutions by near-infrared spectrometry.\u201d&nbsp;&nbsp;<em>Analyst<\/em>&nbsp;114 (7):819-822.<\/p>\n\n\n\n<p>Hirschfeld, Tomas. 1985. \u201cSalinity determination using NIRA.\u201d&nbsp;&nbsp;<em>Applied spectroscopy<\/em>&nbsp;39 (4):740-741. doi: 10.1366\/0003702854250293.<\/p>\n\n\n\n<p>Iwamoto, M., J. Uozumi, and K. Nishinari. 1987. \u201cPreliminary investigation of the state of water in foods by near infrared spectroscopy.\u201d Proceedings of the International NIR\/NIT Conference, Budapest, Hungary.<\/p>\n\n\n\n<p>Maeda, H., Y. Ozaki, M. Tanaka, N. Hayashi, and T. Kojima. 1995. \u201cNear infrared spectroscopy and chemometrics studies of temperature-dependent spectral variations of water: relationship between spectral changes and hydrogen bonds.\u201d&nbsp;&nbsp;<em>Journal of Near Infrared Spectroscopy<\/em>&nbsp;3 (4):191-201. doi: 10.1255\/jnirs.69.<\/p>\n\n\n\n<p>Pollack, G.H., I.L. Cameron, and D.N. Wheatley, eds. 2006.&nbsp;<em>Water and the cell<\/em>. Dordrecht, Netherlands: Springer.<\/p>\n\n\n\n<p>Tsenkova, R. 2008. \u201cAquaphotomics: acquiring spectra of various biological fluids of the same organism reveals the importance of water matrix absorbance coordinates and the aquaphotome for understanding biological phenomena.\u201d&nbsp;&nbsp;<em>NIR news<\/em>&nbsp;19 (1):13-15.<\/p>\n\n\n\n<p>Tsenkova, R. 2009. \u201cAquaphotomics: dynamic spectroscopy of aqueous and biological systems describes peculiarities of water.\u201d&nbsp;&nbsp;<em>Journal of Near Infrared Spectroscopy<\/em>&nbsp;17 (6):303-313. doi: 10.1255\/jnirs.869.<\/p>\n\n\n\n<p>Tsenkova, R. 2010. \u201cAquaphotomics: water in the biological and aqueous world scrutinised with invisible light.\u201d&nbsp;&nbsp;<em>Spectroscopy Europe<\/em>&nbsp;22 (6):6-10.<\/p>\n\n\n\n<p>Tsenkova, R.N., I.K. Iordanova, K. Toyoda, and D.R. Brown. 2004. \u201cPrion protein fate governed by metal binding.\u201d&nbsp;&nbsp;<em>Biochemical and biophysical research communications<\/em>&nbsp;325 (3):1005-1012. doi: 10.1016\/j.bbrc.2004.10.135.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6c34\u306e\u5206\u6790\u306f\u3001\u305d\u306e\u958b\u59cb\u4ee5\u6765\u3001\u8fd1\u8d64\u5916\u5206\u5149\u6cd5\u306e\u5206\u91ce\u306b\u5b58\u5728\u3057\u3066\u3044\u307e\u3057\u305f\uff08Hirschfeld 1985\u3001Grant\u3001Davies\u3001\u304a\u3088\u3073Bilverstone 1989\u3001Iwamoto\u3001Uozumi\u3001\u304a\u3088\u3073Nishinari 1 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","footnotes":""},"class_list":["post-6807","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u30bf\u30f3\u30d1\u30af\u8cea\u5206\u6790 - 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